Gene Therapy · HPAEs Platform

Next-Generation Non-Viral
Gene Delivery Vectors

High-performance transfection reagents engineered for scalable, efficient and reliable gene delivery across cell and gene therapy, viral vector production and protein expression workflows.

Branca Bunús develops advanced HPAE polymer-based technologies designed to help researchers, CDMOs, biotech and pharmaceutical companies accelerate life science breakthroughs with improved transfection performance, scalability and cost-efficiency.

Or contact us at info@brancabunus.com

  • ISO 9001:2015 Certified QMS
  • FDA Type II DMF Holder
  • Trusted by CDMOs & Biotech
  • Dublin, Ireland
About Branca Bunús

Engineering safer and more potent gene delivery technologies

Branca Bunús Ltd is a gene therapy and biotechnology company focused on developing safe gene medicines and potent transfection reagents. Through its HPAEs platform technology, the company advances high-performance non-viral gene delivery vectors for modern life science applications.

  1. 01HPAE platform research

    Polymer engineering for non-viral delivery

  2. 02BrPERfect® reagents

    Next-generation transfection product line

  3. 03Scalable bioprocess

    Workflows from R&D to production-scale

  4. 04Global collaboration

    Biotech and CDMO partnerships worldwide

HPAE Polymer Platform
Hyperbranched Poly(β-amino esters)

Engineered polymer chemistry for non-viral payload delivery.

HPAEs Platform Technology

Toward the next generation of high-performance non-viral gene delivery vectors

HPAE polymer-based delivery, stable complex formation, broad payload compatibility and scalability from R&D to larger production workflows.

/01

Payload Compatibility

pDNA, siRNA, mRNA and CRISPR complexes for targeted delivery applications.

/02

Stable Complex Formation

Easy preparation and super-stable transfection complexes designed to support reliable workflows.

/03

High Efficiency & Viability

Engineered to support improved transfection efficiency while maintaining strong cell viability.

/04

Scalable Performance

Designed for academic research, biotech development and CDMO production environments.

Product · BrPERfect®

BrPERfect® next-generation transfection reagents

A high-performance reagent platform developed to support efficient, scalable and cost-effective transfection workflows.

BrPERfect® is Branca Bunús' next-generation transfection reagent technology, developed through its HPAE polymer-based platform. The reagent is designed for life science teams seeking greater reliability, scalability and workflow efficiency in demanding gene delivery applications.

  • Higher transfection performance
  • Strong cell viability focus
  • Easy preparation
  • Stable complex formation
  • Scalable workflow integration
  • Cost-effective process support
  • Suitable for demanding biotech and CDMO environments
BrPERfect®
HPAE Reagent
Why Branca Bunús

Why leading research and biotech teams choose Branca Bunús

Dedicated Technical Support

Expert technical support and training to help teams succeed at every stage.

Superior Performance

High-efficiency transfection reagents designed to support demanding applications.

Scalable Design

From small academic labs to large-scale CDMO production, the platform is designed to scale with workflow needs.

Cost-Effective Innovation

Premium-quality reagent technology built to help reduce costs while improving process performance.

Custom Solutions

Tailored designs and formulations for targeted delivery of pDNA, siRNA, mRNA and CRISPR complexes.

Industry Adoption

Already adopted by CDMOs and biotech partners in real-world development environments.

Quality · Regulatory · Trust

Built for quality, reliability and regulatory confidence

ISO 9001:2015

Certified Quality Management System

Branca Bunús has achieved certification from the National Standards Authority of Ireland (NSAI) confirming that its Quality Management System meets ISO 9001:2015 requirements.

FDA · DMF #39924

FDA Type II DMF Holder

Branca Bunús has submitted a Drug Master File to the FDA for its lead HPAE polymer-based transfection reagent and received confirmation as a DMF holder, DMF number 39924, from June 2024.

QMS · BrPERfect®

Customer-Centric Quality

The company's QMS covers processes, procedures and responsibilities involved in developing and manufacturing its products, including the BrPERfect® series.

Quality is not a support function. It is part of the platform.

Strategic Partnerships

Strategic partnerships for global biopharmaceutical innovation

Branca Bunús and Duoning Biotech are collaborating on the co-development and commercialization of BrPERfect® next-generation transfection reagents, aiming to deliver high-performance gene delivery solutions for biopharmaceutical companies in China and beyond.

  • Collaboration announced in November 2024
  • Strategic meeting in Shanghai on March 14, 2025
  • Irish–Chinese biopharmaceutical collaboration
  • Co-development of BrPERfect® reagents
Explore partnership opportunities
Dublin · IrelandShanghai · China
Branca Bunús × Duoning Biotech
Co-development & commercialization of BrPERfect® reagents
News & Milestones

Recent milestones

Featured · Award
10 April 2025 · Dublin, Ireland

Professor Wenxin Wang receives 2025 NovaUCD Innovation Award

Professor Wenxin Wang, founder of Branca Bunús and Research Ireland Principal Investigator at the UCD Charles Institute of Dermatology, received the 2025 NovaUCD Innovation Award in recognition of excellence in innovation and commercialization of UCD research.

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Partnership
14 March 2025

Branca Bunús and Duoning Biotech celebrate strategic partnership during Irish ministerial visit to Shanghai

The meeting marked a significant milestone in the strategic partnership focused on co-developing and commercializing BrPERfect® next-generation transfection reagents.

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Partnership
November 2024

Duoning Biotech announces strategic partnership with Branca Bunús

The companies are collaborating on the development, optimization and application of transfection reagents to support upstream bioprocessing innovation.

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Regulatory
June 2024

Branca Bunús gains Type II DMF ID from FDA

Branca Bunús reached a key regulatory milestone with the successful submission of a Drug Master File for its lead HPAE polymer-based transfection reagent.

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Certification
Quality

Branca Bunús achieves ISO 9001:2015 certification

The company's Quality Management System has been certified by NSAI, supporting quality confidence across product development and manufacturing.

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Leadership

Scientific leadership behind the platform

WW

Professor Wenxin Wang

Founder

Founder of Branca Bunús and a leading researcher connected with UCD's Charles Institute of Dermatology and UCD School of Medicine. His work and innovation leadership have contributed to the development and commercialization of advanced gene delivery technologies.

HT

Dr Hongyun Tai

Managing Director & CEO

Managing Director and CEO of Branca Bunús, leading the company's strategy, partnerships and operational growth across international biotech and biopharmaceutical markets.

Contact · Technical Consultation

Start a technical conversation

Speak with the Branca Bunús team about transfection performance, workflow scalability, custom formulations or partnership opportunities.

Email Technical Team
info@brancabunus.com
Headquarters
Lab 4, Building 10, Cherrywood Business Park,
Cherrywood, Loughlinstown, Co. Dublin,
Ireland, D18 T3Y1